Mice breeding

1, improve the utilization rate of male mice.
1-2 weeks of age-appropriate male mice (12-16 weeks old) can complete an in vitro fertilization experiment, which greatly saves the number of male mice and reduces the use of experimental resources.

2, shorten the breeding time.
natural breeding, female mice need 6-8 weeks to be sexually mature before they can be used for mating, while female mice used in IVF can be superovulated in only 4 weeks. IVF only takes 1.5-2 months, compared to the 3 months for a naturally born generation.

3, reduce the individual differences of the same batch of offspring mice.
The birth date of the same batch of offspring mice obtained by in vitro fertilization (IVF) varies by no more than 5 days, reducing the amount of time due to mice weeks of age and batch differences greatly improves the quality of the experiment. For male mice with difficulty in natural breeding, IVF can improve the success rate of breeding.