Is the the highest immune deficiency tool mouse in the world so far;
Compared with NOD-scid mice, there was no residual expression of Prkdc after deletion of exons 2-10 of Prkdc;
There is almost no rejection reaction to human cells and tissues;
A small amount of cells can form tumors, which depends on the cell line or cell type;
No leakage of B lymphocytes.
