Quickmice™ Long Fragment Gene-Edited Mouse Customization

The length of gene editing by traditional technology is mostly less than 5kb, and the longer the edited fragment the lower the success rate. Moreover, to construct a long-fragment knock-in/knock-out mouse model using traditional techniques, the chimeric mice need to be bred and screened for 2-3 generations to obtain the target mice, and the whole process takes more than 10-12 months.

The advantages of long fragment gene editing lie in its ability to overcome certain limitations of traditional gene editing methods.