Tumor drug screening for research
Tumor drug screening for research
Tumor drug screening, also known as anti-cancer drug screening or cancer drug testing, refers to the process of examining various drugs to identify those that can effectively treat tumors. This screening is undertaken to uncover potential therapeutic options for cancer patients. It plays a crucial role in the development of new medications and the enhancement of existing treatments.
The primary goal of tumor drug screening is to identify compounds that can selectively inhibit the growth or kill cancer cells while sparing healthy cells. This approach, known as targeted therapy, aims to maximize treatment efficacy while minimizing side effects. Screening involves subjecting cancer cells, typically sourced from tumor samples to a wide range of drugs to determine their potential effectiveness in killing cancer cells.
Various techniques are employed in tumor drug screening, such as high-throughput screening, which allows for the rapid testing of thousands of compounds. This method enables researchers to identify promising candidates that can then undergo further evaluation for their effectiveness, safety, and potential clinical applications.
MingCeler provides a full range of high-quality preclinical development services for oncology drug screening and validation, including target identification and validation, in vitro cellular assays and screening, in vivo tumor model construction, in vivo pharmacology, pharmacokinetics, pharmacodynamic and basic toxicology assessment.
Depending on the needs of our clients, we can provide deeper mechanistic studies.
Tumor target identification and validation
-In vitro knock-out or overexpression of target genes in genetically engineered cell lines
-In vivo knock-out or overexpression of target genes in mouse models
-In vivo functional assays including tumor growth, metastasis, etc.·
Tumor model
·In situ xenograft
·Intravenous Injections model
·lung metastatic cancer model
·Spleen injection liver metastasis model
·Genetically engineered mouse models
Biochemical and cellular level testing
- Over 260 STR-validated Humanized tumor cell lines which can represent almost all tumor types
- Cell line and primary cell testing
- Metabolomics Testing
- Compound Screening
- Selection of sensitive and tolerant cell lines
Contact Us
LinkedIn: https://www.linkedin.com/company/mingceler/
Tel: +86-181 3873 9432
E-mail: MingCelerOversea@mingceler.com